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L-Biome & L-Pill (Intestinal Health & Antioxidant Anti-Ageing)

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€120,00

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Rich in Pre- and Probiotics
Helps digestion
Stimulates intestinal flora
Promotes healthy ageing
Increases cell protection
Boosts the immune system
Intestinal health is essential for a healthy life. L-Biome accompanies you on your journey star

Ingredients for optimal intestinal health

Research has demonstrated the beneficial effects of extended fasting programs on the microbiome, promoting the growth of beneficial microbes. L-Biome incorporates prebiotic fibers and two essential probiotics, mirroring the post-fasting microbiome. In line with our ProLon philosophy, L-Biome also includes DHA to promote healthy aging of various organs and systems

L-Biome

Bifidobacterium breve B-3

Bifidobacterium breve B-3 promotes weight and body fat reduction, and also helps maintain glucose, insulin and cholesterol levels within a normal range. This is one of the essential microbiota that develops after ProLon 5-day fasting.

Lactobacillus Rhamnosus Hn001

Lactobacillus Rhamnosus Hn001 supports healthy digestive and intestinal function, promotes healthy intestinal barrier integrity, supports a healthy intestinal immune axis and promotes digestive comfort and healthy nutrient absorption. This is one of the essential microbiota that flourishes after ProLon Fasting Nutrition.

Chicory root: Prebiotic

L-Biome also contains prebiotics such as chicory root, which can support the proper functioning of the gastrointestinal tract, promote the beneficial production of short-chain fatty acids by a healthy gut microbiota and provide functional prebiotics that can support the growth of bifidobacteria and Lactobacillus species in the gut microflora.

DHA

With EFSA approval for promoting cardiovascular health, brain health and eye health within normal limits at all stages of life. DHA is a structural component of the human brain and the eye. DHA can also positively influence the gut-brain axis, promote intestinal wall integrity and support the body's immune health.

Lysine

Lysine is an amino acid essential to life. It stimulates tissue-building processes and plays a key role in periods of stress (intense physical effort, injuries, burns, surgery). It is indispensable for numerous biochemical regulations, but above all for the development of the body and the growth of muscle mass. Supplementation with this amino acid is particularly indicated in cases of acute and recurrent herpes.

star The L-Pill is the only supplement that I would take - Dr. Valter Longo star

Ingredients for healthy aging

The quality and pace of our biological aging are key determinants of a long and healthy life. L-Pill's strength lies in its unique combination of four natural ingredients that have been consumed by millions of people and studied for their potential benefits in healthy aging.

L-Pill

DHA

With EFSA approval to promote cardiovascular health, brain health and eye health within normal limits at all stages of life. DHA is a structural component of the human brain and retina. DHA can also positively influence the gut-brain axis, promote intestinal wall integrity and support the body's immune health.

Wasabi Japonica

Wasabi japonica rhizome/root is known to naturally target a gene regulatory network involved in cell protection and supporting liver health and detoxification, healthy immune function and brain health.

Cane sugar extract

Very rich in polyphenols, flavonoids and proanthocyanins, it promotes metabolic health (supporting glucose levels), supports healthy antioxidant status of lipids, proteins and mitochondria, as well as healthy immunomodulation secondary to daily activity, exercise and aging.

Green tea extract

Organic green tea leaf extract from camellia sinensis, which includes catechins containing ECGC and caffeine, promotes sustained energy, may support healthy antioxidant status, encourages cellular protection, metabolic function and cardiovascular health, and therefore promotes brain health and immune system function .

Lysine

Lysine is an amino acid essential to life. It stimulates tissue-building processes and plays a key role in periods of stress (intense physical effort, injuries, burns, surgery). It is indispensable for numerous biochemical regulations, but above all for the development of the body and the growth of muscle mass. Supplementation with this amino acid is particularly indicated in cases of acute and recurrent herpes.

WHY L-BIOME & L-PILL

Innovation meets nature.

Our L-Biome guarantees an optimal dosage of these ingredients in a safe and effective way. DHA is bound to the essential amino acid L-lysine to form a salt, making it more easily assimilated by the body and increasing its effectiveness.

Our L-PILL guarantees optimal dosage of these ingredients, safely and effectively. DHA is bound to the essential amino acid L-lysine to form a salt, making it more easily assimilated by the body and increasing its efficacy.

HOW IT WORKS

How and when to use it

L-Biome can be used daily by anyone between the ages of 18 and 80. It is best used after consuming one of the ProLon products: the 5-day fasting diet, the one-day ReSet nutrition, the Fast Bar nutrition program or the Fasting shake. You can stop and start again at any time. If you have any health problems, consult your doctor before taking L-Biome. Do not take L-Biome if you are allergic to one of its ingredients.

L-Pill: Take two capsules a day before or during a meal. You can stop and start again at any time. If you have any health problems, consult your doctor before taking L-Pill. Do not take L-Pill if you are allergic to any of its ingredients.

Some Morinaga B-3 Select References:

  • Minami, J.I., Kondo, S., Yanagisawa, N., et al., 2015. Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial. Journal of Nutritional Science, 4.

  • Minami, J., Iwabuchi, N., Tanaka, M., et al., 2018. Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Bioscience of Microbiota, Food and Health, pp.18-001.

  • Inoue T, Kobayashi Y, Mori N, Sakagawa M, et al., 2018. Effect of combined bifidobacteria supplementation and resistance training on cognitive function, body composition and bowel habits of healthy elderly subjects. Benef Microbes. 2018 Dec 7;9.


LactoB HN001 Lactobacillus rhamnosus strain: Some Select References:

  • González-Hernández LA, Jave-Suarez LF, Fafutis-Morris M, Montes-Salcedo KE, Valle-Gutierrez LG, Campos-Loza AE, Enciso-Gómez LF, Andrade-Villanueva JF (2012) Synbiotictherapy decreases microbial translocation and inflammation and improves immunological status in HIV-infected patients: a double-blind randomized controlled pilot trial. Nutr J 11:90.

  • Mokkala K, Pussinen P, Houttu N, Koivuniemi E, Vahlberg T, Laitinen K. (2018) The impact of probiotics and n-3 long-chain polyunsaturated fatty acids on intestinal permeability inpregnancy: a randomised clinical trial. Beneficial Microbes 9(2): 199-208

  • Kruger MC, Fear A, Chua WH, Plimmer GG, Schollum LM (2009) The effect of Lactobacillus rhamnosus on mineral absorption and bone health in growing male and ovariectomised female rats. Dairy Science & Technology 89:219-231.

  • Tannock GW, Taylor C, Lawley B, Loach D, Gould M, Dunn AC, McLellan AD, Black MA, McNoe L, Dekker J, Gopal P, Collett MA (2014) Altered transcription of murine genes induced in the small bowel by administration of probiotic strain Lactobacillus rhamnosus HN001. Applied and Environmental Microbiology 80:2851-2859

  • Miller LE, Ouwehand AC (2013) Probiotic supplementation decreases intestinal transit time: Meta- HN019, analysis of randomized controlled trials. World Journal of Gastroenterology 19:4718-4725


Inulin / Fructooligosaccharide Select References:

  • Shah BR, Li B, Al Sabbah H, Xu W, Mráz J. Effects of prebiotic dietary fibers and probiotics on human health: With special focus on recent advancement in their encapsulated formulations. Trends Food Sci Technol. 2020 Aug;102:178-192.

  • den Besten G., van Eunen K., Groen A.K., Venema K., Reijngoud D.-J., Bakker B.M. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. Journal of Lipid Research. 2013;54(9):2325–2340.

  • Dewulf E., Cani P., Claus S., Neyrinck A., Puylaert P., Glenn G.…Delzenne N. INULIN-TYPE fructans with prebiotic properties lessen endotoxemia and modulate host metabolism by changing gut microbiota composition in obese women: 749 accepted poster. Obesity Facts. 2012;5:200–201.

  • Dewulf E.M., Cani P.D., Neyrinck A.M., Possemiers S., Van Holle A., Muccioli G.G.…Sohet F.M. Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice. The Journal of Nutritional Biochemistry. 2011;22(8):712–722.

  • Nicolucci A.C. Prebiotics reduce body fat and alter intestinal microbiota in children who are overweight or with obesity. Gastroenterology. 2017;153(3):711–722



BASF Algal Oil DHA (200 mg dose): Select References:

  • Costantini L, Molinari R, Farinon B, Merendino N. Impact of Omega-3 Fatty Acids on the Gut Microbiota. Int J Mol Sci. 2017 Dec 7;18(12):2645 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751248/

  • Jayapala H, Lim SY. N-3 Polyunsaturated Fatty Acids and Gut Microbiota. Comb Chem High Throughput Screen. 2022 Jul 1. doi: https://pubmed.ncbi.nlm.nih.gov/35786331/

  • Rousseau G. Microbiota, a New Playground for the Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Diseases. Mar Drugs. 2021 Jan 23;19(2):54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931107/

  • Stillwell W, Wassall SR. Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids. 2003;126(1):1-27.

  • Serhan CN. Novel Pro-Resolving Lipid Mediators in Inflammation Are Leads for Resolution Physiology. Nature. 2014 Jun 5; 510(7503): 92–101.

  • Kotani S, Sakaguchi E, Warashina S, et al. Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction. Neurosci Res 2006;56(2):159-64.

  • Innes JK, Calder PC. Marine Omega-3 (N-3) Fatty Acids for Cardiovascular Health: An Update for 2020. Int J Mol Sci. 2020 Feb 18;21(4):1362.

  • SanGiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res. 2005;24(1):87-138

The Scientific Research that supports the Longevity Supplement:

https://n.neurology.org/content/early/2022/11/22/WNL.0000000000201541

Costantini L, Molinari R, Farinon B, Merendino N. Impact of Omega-3 Fatty Acids on the Gut Microbiota. Int J Mol Sci. 2017 Dec 7;18(12):2645 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751248/

Jayapala H, Lim SY. N-3 Polyunsaturated Fatty Acids and Gut Microbiota. Comb Chem High Throughput Screen. 2022 Jul 1. doi: https://pubmed.ncbi.nlm.nih.gov/35786331/

Rousseau G. Microbiota, a New Playground for the Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Diseases. Mar Drugs. 2021 Jan 23;19(2):54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931107/

Stillwell W, Wassall SR. Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids. 2003;126(1):1-27.

Serhan CN. Novel Pro-Resolving Lipid Mediators in Inflammation Are Leads for Resolution Physiology. Nature. 2014 Jun 5; 510(7503): 92–101.

Kotani S, Sakaguchi E, Warashina S, et al. Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction. Neurosci Res 2006;56(2):159-64.

Innes JK, Calder PC. Marine Omega-3 (N-3) Fatty Acids for Cardiovascular Health: An Update for 2020. Int J Mol Sci. 2020 Feb 18;21(4):1362.

San Giovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res. 2005;24(1):87-138